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" ... How did this theory arise? Gastrointestinal symptoms like constipation can occur relatively early on in the course of Parkinson's Disease. Also, cutting the vagus nerve used to be a treatment for stomach ulcers. The vagus connects the gut to the brain. There has been the observation that those who underwent such vagotomies seemed to have lower likelihood of eventually developing Parkinson’s. But again, the gut-brain connection for Parkinson's Disease is still a theory without enough strong scientific evidence yet. ... "