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" ... Indications of treponemal disease are well known in the New World prior to Columbus, particularly in the east and southwest of the U.S., but there is currently no clear evidence that venereal syphilis existed in the Americas until after European colonization. Skeletons with bejel or yaws - the other two treponemal diseases that cause bony reactions - are not found very often in archaeological settings in the ancient U.S. Most of the cases come from more recent time periods, after people began to domesticate plants and animals, and to stay in one place for longer periods of time. This increase in sedentary living presumably led to the evolution of a variety of diseases and the increased opportunity to pass them on. ... "