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" ... David Roy and colleagues report on their experience with 43 NAVR patients deemed ineligible for surgery who underwent TAVI with the CoreValve (Medtronic) device at 14 centers in Europe and Israel. The high risk group had a mean age of 75, and many patients had severe comorbidities. Three-fifths of the group had degeneration of the aortic valve leaflets. The device was implanted in all but one of the patients, though 8 patients required a second valve during the procedure. One patient converted to open surgery. In 35 cases the device was implanted via transfemoral access; the remaining cases were performed via subclavian access (4), direct aortic access (3), and carotid access (1). ... "
" ... Edwards said the Sapien XT will be immediately available along with its accompanying transfemoral, transapical, and transaortic delivery systems. ... "
" ... In performing the TAVR procedure, the valve is crimped onto the catheter-based transfemoral delivery system, which is inserted into the body through a small cut in the leg. Once delivered to the site of the patient's diseased valve, the Edwards SAPIEN valve is expanded with a balloon and immediately functions in place of the patient's native valve. ... "