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" ... The broad recognition that the immune system plays a crucial role in the control of tumors has enabled -- and more appropriately, obliged -- researchers to integrate the accumulated knowledge from multiple disciplines: cancer biology (think disorders of signal transduction), immunology, and a field of study that focuses on the so-called “tumor microenvironment” (routinely called TME), the localized environment where cancer grows, and which seem to have distinct and relevant properties, particularly a tendency to be profoundly immunosuppressive. ... "
" ... The three mechanisms by which a bacterium can acquire genetic information horizontally, rather than... [+] vertically (through reproduction), are transformation, transduction, and conjugation. ... "