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" ... The fact that many approvals have sped through the review process, however, does not mean that the FDA's standards have dropped. On May 2, the agency convened an expert panel to discuss whether it should approve tivozanib, an experimental kidney cancer treatment being developed by tiny AVEO Pharmaceuticals of Cambridge, Mass. Tivozanib's selling point was that it was supposed to have fewer side effects than the other gene-targeted cancer drugs that have transformed the treatment of kidney cancer. But at the FDA panel the agency pointed out that patients who received tivozanib died sooner than those who had received another drug, Nexavar. And Pazdur showed why he has caused so many biotech executives nightmares over the years. ... "