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" ... Personally, it was a reminder to me of the forces and events that have shaped my own sensibilities, political and otherwise. In fact, I’d group thalidomide with the Vietnam War and the civil rights movement as formative impacts in my life. I’m particularly haunted by the medium through which those impacts were made. Dead soldiers and civilian babies, hoses turned savagely on peaceful protesters, limbless children held fast by agonized parents…Then as now, visual images mold our perceptions and transform our lives. ... "
" ... Thalidomide holds a special place in drug discovery lore. Initially marketed in Europe in the 1950s to help pregnant women overcome morning sickness and to help them sleep, thalidomide was found to be a teratogen – a compound that interferes with the growth of a fetus thus leading to birth defects. Thousands of babies were born with severe deformities as a result of this drug. Fortunately, the FDA never approved thalidomide thanks to the diligence of FDA reviewer Dr. Frances Kelsey. Despite being approved in Europe, Kelsey demanded additional test data, delaying FDA approval and thereby sparing Americans the misfortunes experienced in Europe. As a result of her actions, Kelsey was awarded the President’s Award for Distinguished Civilian Service by President John Kennedy. In addition, due to the public alarm that arose from this horror, Congress passed the Kefauver-Harris Drug Act in 1962 that revamped and toughened the U.S. drug approval process. ... "