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" ... What is notable about this list is that all of these drugs come from small companies. While the potential financial returns from a drug in this area don't necessarily appeal to big pharma, smaller companies clearly see opportunities. One company that has staked its future in this area is Cubist, the innovator behind the last two entrants on the Infectious Disease News list. (Since the list was published, Cubist received FDA approval for tedizolid, which is being marketed under the trade name Sivextro.) Cubist’s Chief Scientific Officer, Dr. Steve Gilman, a former Pfizer colleague, recently told me that 75% of their scientists are focused on novel antibiotics and they will spend over $400 million this year in this area. Gilman is proud of the fact that they have a broad research program looking for treatments for both gram negative and gram positive infections. ... "