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" ... But last month, all 3 trials paused enrollment of the critically ill subgroup after data demonstrated that full-dose anticoagulation initiated in the ICU was not beneficial and may have caused harm in some patients. One might infer that safety was likely a factor in the decision to pause enrollment in ICU patients, with consideration for potential harm (caused by excessive bleeding). ... "
" ... However, every social and demographic subgroup includes significant numbers of disabled people. Anyone can have a distinct or marginalized identity, and be disabled as well. This affects more than just statistics. It means that the disability community itself is incredibly diverse. And the experience of disability adds extra dimensions and cross-cutting perspectives to other demographic populations. ... "
" ... Precision medicine’s promise is to determine for each individual patient or subgroup if a drug will work or not, and whether it will produce adverse events. Among other pieces of information, it does this based on pharmacogenomics. Here, pharmacogenomics refers to how a person’s genetics affects his or her response to a drug. In this regard, an individual’s genetic makeup can determine how effective a medication will be, whether dosing changes will be needed, or whether a different medication should be prescribed. ... "
" ... Whether mental healthcare is part of the first subgroup getting the vaccine will be up to each state’s interpretation of the guidelines, Bahta said. Some may decide that mental health and substance use providers belong in the first phase, “Phase 1a,” while others might group them in the “1b” category, which the committee has not yet voted on but may include essential workers like bus drivers, teachers and police officers. “There will be a multitude of variations on how this plays out,” she said in an email. ... "
" ... “We are hopeful that we may have identified one such subgroup, and that future research will uncover other… explanations, potentially involving the gut microbiome.” ... "