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" ... This was a small study of 33 participants who were experiencing psychotic symptoms. A smaller group of healthy participants served as a control group. Half the psychosis group was given one 600 mg oral dose of CBD (a dose that was "previously effective in established psychosis" according to the study), the other half received an identical placebo capsule. The control group didn't receive any drug. Then all of the participants completed a memory task designed to engage three brain areas that have been linked to the onset of psychosis (specifically the striatum, medial temporal cortex, and midbrain) while their brains were examined with an fMRI scanner. ... "
" ... Two hours later, when inflammation was peaking, the participants played a game designed to build their anticipation of a cash reward while their brains were scanned in an fMRI machine. The point of this was to evaluate activity in a brain area called the ventral striatum (VS), a core part of the brain’s dopamine-fueled “reward center.” ... "