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" ... 'That base chemical [pyrimethamine] happens to be incredibly inexpensive and the most expensive part of building this formulation is labor, believe it or not," says Baum. ... "
" ... Valeant and Turing bought monopoly positions in old drugs that faced no direct competition in the United States. But they are important medicines. Nitropress, used to treat patients whose blood pressure has risen to dangerous levels, jumped in price by more than three times to $805 per vial immediately after Valeant’s purchase, while Isuprel, which addresses heart rhythm problems, soared more than six times to $1,346 per vial. Turing purchased a 63-year-old anti-parasite pill, Daraprim (pyrimethamine), and took the even more brazen step of inflating its price by more than 5,000 % to $750/tablet. The drug treats toxoplasmosis, an infection from a common parasite found in cats, which can be deadly for babies in utero and present serious symptoms, including seizures, lung complications and blurred vision for those with compromised immune systems. In the United States, the market is small enough that no company produces a generic alternative. ... "