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" ... Neil Nedley, M.D.: Up to 1 in 3 patients that an Internal Medicine physician consults suffers from either depression or anxiety. Many gastrointestinal symptoms are actually from depression or anxiety, and there is also a powerful gut-brain connection. Many of the neurotransmitters produced in the bowel are also produced in the brain utilizing similar biochemical pathways. Most antidepressants or anti-anxiety drugs do not help the brain or gut produce the neurotransmitters short in the brain or bowel. They just block the vacuum cleaners (re-uptake channels) in the releasing neuron, eventually depriving the neuron of the very substance it needs. With my background in biochemistry, I realized there were simpler, more effective ways to help the brain or gut produce the lack of neurotransmitters, avoiding the side effects of the vacuum cleaner "pluggers" and thereby producing more effective and lasting solutions. ... "