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" ... Capabilities (phenotypes) can be expressed if the right skills (genes) are present — along with the suitable environment, rewards and challenges. This is why it is extremely important to precisely decode the talent genome and recognize the factors that could enable a phenotype's full potential. ... "
" ... Frank Nothaft, Technical Director Healthcare and Life Sciences for Databricks notes that Healthcare and life sciences (HLS) firms have been among the earliest adopters of distributed and Cloud computing. This is driven by a need to support highly collaborative scientific computing and drug discovery activities. “Large pharmaceutical firms were at the forefront of early movement of healthcare and life sciences into the Cloud” says Nothaft. This was driven by work on genomic databases, phenotypes, genetic markers, drug discovery, and the need to reduce the high costs of creating new drugs. While mainstream industries like financial services have been among the heaviest users and investors in data management capabilities, they have been slower to adopt Cloud computing. ... "
" ... Three companies – including two with leading PCSK9 programs – have set out to replicate the success of the PCSK9 story, each in a slightly different ways. In each case, the key issue is the starting point – where do you find the phenotypes of interest? ... "
" ... Trivisvavet breaks Inari’s technologies into two categories. One is machine learning, which Trivisvavet calls predictive design. “This technology allows us to understand the interconnectivity between genes, the pathway of how the genes interact with one another,” explains Trivisvavet. The second part of the company’s core technology is its gene-editing toolbox. Composed of CRISPR-based tools, this platform enables Inari to express the most useful phenotypes or characteristics of a given crop. The unexplored potential of crop gene expression points to limitless possibilities. “When we count the number of genomes, plants are much more complex than humans,” says Trivisvavet. ... "