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" ... As I observed pure volatility and market movement in real time, I was struck by how peer traders--and the financial press--struggled to explain the upward market trajectory. Sometimes it was attributed to central bank expectations; other times to geopolitical events or data releases. More parsimoniously, colleagues steeped in finance referred to "value" or "momentum" factors. None of those accounts, however, truly explained what was happening: why volume was now influencing price more than usual and why that was generating superior forward returns. ... "
" ... While some critics of RWE methods worry about the ethics of subjecting patients to interventions not evaluated in a tradition RCT, Schneeweiss worries about the ethics of unnecessarily exposing patients to potential randomization when the data required could have been obtained, more parsimoniously, by intelligently leveraging existing claims or other data. ... "