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" ... The Long-Term Odanacatib Fracture Trial (LOFT) is a randomized, double-blind, placebo controlled trial of 16,713 women 65 years of age or older, diagnosed with osteoporosis, who have been postmenopausal for five years or more. Study volunteers were randomized to placebo or 50 mg weekly of odanacatib. Women in both groups received vitamin D at 5,600 IU/day and calcium at up to 1,200 mg/day, if required. The study is being conducted in 387 centers in 40 countries in the Americas, Europe, and the Asia-Pacific region. ... "