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" ... Hostetler says that NIAID officials were aware of his previous work on making antiviral nucleoside drugs more orally bioavailable to the body. If he was willing to use some of his chemical know-how to make cidofovir a better agent against smallpox, they were willing to give his laboratory $100,000 to try. ... "
" ... “The idea is to find the best horse in each of the categories. Antivirals plus host immune response modulation makes a lot of sense, but we need to find the best therapeutic in each category, for the right patient population.” says Ramaswamy, who studied biology at Harvard, was a hedge fund analyst and earned a Yale law degree before he began building his innovative biotech firm in 2015. “For antivirals, is it a nucleoside, or an antimalarial which prevents viral propagation in a different way? For immune response modulation, is it anti-IL-6 or anti-GM-CSF? The answer may differ by patient population. Let’s sort those questions out quickly.” ... "