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" ... Based on lab studies reported so far, nivolumab-responsiveness could not be predicted based on pathological features of the tumors, such as levels of PDL-1. The antibody was given by intravenous infusion every other week. Toxicity was also better in the nivolumab arm: grade 3 or 4 adverse effects were noted in 19% of that group, compared with 37% of the everolimus recipients. No deaths were attributed to nivolumab. Side effects from nivolumab, as reported in this trial, included fatigue, nausea and itching. Serious effects were mainly related to low blood counts, such as anemia. ... "
" ... Bristol-Myers Squibb received approval in Japan for their anti-PD-1 drug, Opdivo (nivolumab), leading to speculation that it might be the first to be approved in the U.S. ... "