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" ... At Sciele he'd become fascinated by another of its products: a spray form of nitroglycerin used by heart patients to stop attacks of chest pain. "Patients loved it," Kapoor says. "I started looking into the sprays, and to my surprise, I found it was the only product that was sold as a spray in this country." What other drug would work well as a spray? Well, fentanyl, which cancer patients needed for rapid relief of pain. The idea wasn't a fit for Sciele, so Kapoor brought it to Insys, a small company he'd founded in 2002. Fourteau joined the board in 2011, and Insys decided on a sales-force strategy much like Sciele's, with young, aggressive salespeople. Asking them to sell a potentially deadly narcotic on an incentive plan created a powder keg primed to explode. ... "
" ... The most commonly encountered nitrate is nitroglycerin, used for acute management of chest pain due to angina. Isosorbide mononitrate is another such drug, but is used for long-term prevention of angina. It's sold under the trade name, Ismo®, but is more commonly used in the combination drug, Bidil® (co-formulated with hydralazine). ... "