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" ... Migraine is a common, chronic neurovascular disorder characterized by severe, debilitating headaches that can last for several hours, or even days, and can recur as frequently as daily. Migraine is often accompanied by nausea, vomiting and other neurological symptoms, such as light and noise sensitivity, as well as visual aura. An estimated 10-15% of Americans suffer from migraines. Women are particularly at risk. Migraine is in the top ten diseases in terms of highest cause of disability. Additionally, management of the disease presents a substantial economic burden related to lost productivity and use of healthcare resources, such as physician and emergency room visits. ... "