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" ... There, you'll learn about naloxegol, the internationally agreed-upon generic name for Movantik brand name, and how it's a "peripherally-acting, mu-opioid receptor antagonist," or PAMORA. What this means is that the drug blocks mu opioid receptors outside of the brain and spinal cord. The idea is that, at recommended doses, the drug blocks opioid-induced constipation without blocking pain control that's mediated by the same receptors in the brain and spinal cord. ... "