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" ... Earlier this week, Merck entered into an agreement to acquire Tilos Therapeutics for up to $773 million. Tilos is a privately held biopharmaceutical firm developing therapeutics that target the latent transforming growth factor beta (TGF-β) complex. TGF-β plays a role in regulating cellular activities, such as cell growth, differentiation, and motility. Unregulated TGF-β signaling can lead to inflammation, cancer, and autoimmune disorders. Tilos has been involved in the development of potential treatments of, among other diseases, various cancers and autoimmune disorders. ... "