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" ... Cardarine (GW 501516) is NOT a SARM (selective androgen receptor modulator). Rather it is a Peroxisome proliferator-activated receptor beta (PPAR) agonist which binds to those receptors. This means the activity in the gene is changed, causing a shift in how energy is put out. This translates into an ability to push harder and longer when it comes to endurance, without becoming winded. This can help you not just with cardio/running, but also in the weight room since you can push out another repetition and workout for longer without becoming tired. ... "
" ... Other issues also loom for the ALKS-3831 clinical program. First of all, Alkermes will need to run a full trial in schizophrenic patients to demonstrate that the addition of its opioid receptor modulator doesn’t impact the antipsychotic activity of olanzepine. The same is true for the safety of ALKS-3831 – does the combination of these two drugs result in any new side-effects? My guess is that the FDA will require a full phase 3 program to answer these questions. ... "