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" ... Despite the potential forĀ a setback, the drug is expected to be a minor product for Pfizer, given that the FDA estimates only 5,000 to 10,000 people worldwide are affected by the affliction. Of course, Pfizer would have proceeded anyway, since the FoldRx acquisition involved proprietary technology used to target diseases caused by so-called protein misfolding. And in doing so, the drugmaker can also point its pursuit of a treatment for a rare disease. Tafamidis is already approved in Europe. ... "
" ... One example is our recent $58 million collaboration with The Cystic Fibrosis Foundation Therapeutics (CFFT) on a research program targeting the most common gene mutation in CF. CFFT is focused on accelerating the best science with the greatest chance of helping CF patients. We are extremely proud of this partnership and see it as important validation of our key capabilities in protein misfolding, as well as our partnership strategy. CFFT will fund pre-clinical research at Pfizer for up to six years, with the goal of advancing multiple clinical candidates that will require further investment from Pfizer to get them to patients suffering from this devastating disease. The CFFT will receive royalties on any potential commercial sales of future products, enriching their ability to continue to invest in research. ... "