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" ... The most recent Supreme Court challenge to capital punishment involved the recent substitution of midazolam (a benzodiazepine) for the time-tested sodium thiopental and sodium pentobarbital (both older barbiturates). When these drugs were no longer available (because one company stopped making it or refused to sell in the U.S. for executions), attention turned to using midazolam. While intravenous midazolam is used for medical procedures (you might also know it a Versed), it doesn't produce the depth of anesthesia as do the barbiturates. As a result, some executions have been prolonged or the prisoner has appeared to awaken during the procedure. ... "
" ... Within 24 hours, the participants who’d received ketamine reported significant changes in symptoms compared to those receiving midazolam. They had a reduction in suicidal thoughts, depressive symptoms, and fatigue. In fact, the participants who didn’t respond to midazolam were later given ketamine, and they showed the same improvements. ... "