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" ... A month after our visit, one of her dearest friends from New Jersey came out for a week. But she was already fading. Although the Taxol worked on her tumors, she had developed peripheral neuropathy, a common side effect of Taxol and related drugs that work on the microtubules of cells. She described the combination of pain, numbness and tingling in her feet like walking on marbles. Reluctantly, she had to discontinue the Taxol treatment. ... "
" ... Normally, tau protein helps build and stabilize the microtubules that help form the cytoskeleton of nerve cells. The hypothesis was that head trauma can cause the leakage of tau protein out of the nerve cells and result in accumulations of tau protein in the brain. For years, it was thought that woodpeckers would not have such accumulations because their brains were more resistant to trauma. But this finding does change the thinking. Is the tau protein actually helping protect them against brain damage or do woodpecker brains react to or clear away tau protein differently from the way humans do? In other words, where does tau protein fall in the pecking order? ... "
" ... Sperm have an egg-shaped head full of the father’s DNA and a long, whip-like tail that lashes around chaotically to propel the sperm forward. Inside the tail is bundle of microtubules, each of which is dotted with molecular motors called dynein proteins. The dyneins flex back and forth like little legs, making the microtubules slide laterally past each other. That makes the tail bend, which drives the sperm forward. ... "