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" ... Maltitol is made in labs from the sugar maltose, which like many sugars is two rings made of oxygen and carbon joined together. To make a sugar alcohol, chemists break one of those rings apart. The remaining ring still activates the sweet sensors in our taste buds and our bodies can use it for energy. The broken ring, on the other hand, passes through the digestive system largely untouched. Which means: fewer calories. And also: very unpleasant side effects. ... "
" ... The lutung-type cells did not respond to any of the sugars, suggesting that these monkeys would not be able to taste sweet things. A control experiment with the same genes from Japanese macaques did show a response to the sugars, especially maltose. The team found mutations in the lutung TAS1R2 and TAS1R3 genes. ... "