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" ... "We may have had it backwards for the past 30 years," says Kathiresan. For years, researchers were infatuated with another blood test, for "good cholesterol" or high-density lipoprotein, called HDL. The idea was that HDL somehow protected people against heart attacks. "In medical school, we were taught to pay attention to HDL and ignore triglycerides," says Ethan Weiss, a cardiologist at UC-San Francisco. ... "
" ... Resveratrol might help prevent damage to blood vessels, reduce low-density lipoprotein (LDL) cholesterol (the "bad" cholesterol) and prevent blood clots. ... "
" ... This was certainly a very provocative result. At the time, statins like Zocor and Pravachol were demonstrating great low density lipoprotein (LDL-c) lowering capability, and were soon to be proven to reduce heart attacks and strokes. Yet, the Framingham Heart Study showed that raising HDL-c had even better potential in reducing CV events. Could inhibiting CETP in heart patients with lipid abnormalities mimic the situation seen with people with a CETP deficiency? If yes, CETP inhibitors could prove to be more important than statins in the fight against heart disease. ... "
" ... Topol also has concerns that the placebo may have raised cholesterol and c-reactive protein. “They happened to have a placebo that’s not inert,” he says. That won’t explain the results, he says, but it’s also not helping to sort things out. He says he’s not comforted by an analysis showing that the results hold up when researchers analyzed them with just the patients in the placebo group whose low-density lipoprotein (LDL, the "bad cholesterol") went up, or just those in whom LDL stayed flat. “That’s just one way of looking at it,” he says. “It probably should be looked at in multiple ways." Still, he says, "At the end of the day, I don’t think that the main explanation is that the placebo is the problem. I doubt it was the singular problem. It was contributing.” ... "
" ... Yes, there is some evidence that moderate amounts of alcohol could potentially improve your circulation and metabolism such as raising your levels of your "good" cholesterol (high-density lipoprotein or HDL), increase your body's sensitivity to insulin, and improving factors (e.g., tissue type plasminogen activator, fibrinogen, clotting factor VII, and von Willebrand factor) that make your blood less likely to form small blood clots that could lead to strokes and heart attacks. Yes, many alcoholic drinks may have different nutrients such as wine having antioxidants and beer having riboflavin, thiamin, magnesium, and calcium. Yes, some amounts of alcohol may help you relax or facilitate social interactions (i.e., liquid courage.) Plus, some mixed drinks can have little umbrellas. Indeed, alcohol, when drunk in moderation, could have some benefits. ... "