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" ... The critical component to Vukelic's approach is that the induction of low-density plasma causes ionisation of water molecules within the cornea. This ionisation creates a reactive oxygen species, that is, a type of unstable molecule that contains oxygen and that easily reacts with other molecules in a cell. This in turn interacts with the collagen fibrils to form chemical bonds, or crosslinks. The selective introduction of these crosslinks induces changes in the mechanical properties of the treated corneal tissue. ... "