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" ... But what was the result of these unedited introns? A careful examination of sequence data showed that JARID2 and JMJD3 each retained an intron that contained a stop codon. These premature stop codons either halt production of the protein or they cause smaller proteins to be constructed. Such abbreviated proteins don't work normally: their functionality is either reduced, altered, or completely abolished. ... "
" ... Not correct. Here's the facts: when making DNA into a protein, the cell copies DNA into RNA. Big chunks of the RNA are spliced out and discarded. Those are "introns." What remains is "exons." That's it. The nucleotides that code for amino acids are contained within the exons, but they are not the same thing. It's not unusual for 25% or even 50% of the nucleotides in the exons to be ignored when making amino acids. ... "