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" ... **For research oriented readers, the Ki values against human 5-HT2 receptors expressed in HEK293 cells were: 15 ± 1 nM at 5-HT2C, 112 ± 7 nM for 5-HT2A, and 174 ± 32 nM at 5-HT2B. Lorcaserin was more selective in receptor-stimulated inositol phosphate accumulation in the same cells. The EC50 values were: 9 ± 0.5 at 5-HT2C, 168 ± 11 at 5-HT2A, and 943 ± 90 at 5-HT2B. The maximum effect was 100% that of 10 μM serotonin at 5-HT2C and 5-HT2B receptors but only 75% at 5-HT2A receptors. ... "