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" ... However, in a recent conversation, Meanwell shared that he doesn’t plan to compete solely on these benefits of inclisiran. Rather, he plans to broaden access to inclisiran via a significantly lower price as compared to the established agents. Part of his move to this position was based on studying the changes in the top ten selling drugs of 2000 vs. those of 2015. The former group, which included drugs like Lipitor, Celebrex and Zoloft, generated sales of $34 billion (inflation adjusted). The 2015 list, which included Humira, Harvoni and Embrel, amassed $84 billion. These data are not all that shocking. But what surprised him was that the $34 billion spent in 2000 benefited a target population of 413 million patients, whereas the top ten selling drugs of 2015 only benefited 54 million. Basically, the top ten drugs of 2015 are targeting one-eighth of the 2000 population at 2.5X the cost. He believes that such a trend is unsustainable for healthcare in America. ... "
" ... “This is a momentous occasion that further reinforces our confidence in the tremendous potential of inclisiran to fundamentally change the treatment of cardiovascular disease.” ... "