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" ... Perls and Handelsman’s critique of testosterone marketing comes just weeks after the U.S. Food & Drug Administration issued tough new rules for the companies that market the hormone treatment. The agency demanded labels be revised make it clear the drugs are only for patients with diseases like hypogonadism or injuries that cause severely low levels of testosterone, and that replacement therapy may raise the risk of cardiovascular problems. Furthermore, the agency ordered testosterone makers to conduct post-marketing research to better elucidate testosterone's risks. ... "