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" ... Alexion ($23 billion, -3% YTD) is a pharma company best known for Soliris, a drug used to treat atypical hemolytic uremic syndrome and paroxysmal nocturnal hemoglobinuria – two rare disorders. The company has seen demand for Soliris grow, with revenues almost doubling from $2.6 billion in 2015 to $5 billion in 2019. Alexion’s pipeline also looks strong, with multiple drugs in phase 3 clinical trials including Ultomiris, which is its next-generation drug for PNH. ... "
" ... In a major hemolytic transfusion reaction, the recipient’s immune system vigorously attracts the donated blood. The cells are ripped apart, tons of bad chemicals are released, and the person gets super sick. The kidneys can fail… first reddish urine then shutdown. The person can develop a severe flu like illness. They can go into shock and ultimately die. Mortality is high without treatment and considerable even with it. ... "