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" ... Another paper found that gliadin causes zonulin production, which increases intestinal permeability to large molecules, and that this happens in all people. It has nothing to do with good or bad metabolism, however, as this happens to everyone even if they get zero symptoms; nor does that article mention if any other foods have the same effect. Zonulin was only recently discovered, so we don’t know much about it yet, nor do we know how accurate the past work is. In any case, whether a food produces it or not does not mean we cannot digest the food, just that some people react badly to the normal breakdown product. The fault lies in the mutation in those who feel ill, not in the food or in the human digestive system. ... "