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" ... In an ideal world, every couple at risk for having a baby (or, any many cases, another baby) with an inherited disease could take steps to eliminate that risk without exposing that child to unknown “off-target” effects (and bypass the ethical issues surrounding germline modification) and be able to afford to do so. ... "
" ... When it comes to germline genome editing (i.e. not for reproduction), only 40 out of 96 countries have specific policies to address this, where 23 countries prohibit this research, and 11 explicitly permit it. ... "
" ... “In the future, I think we need to far expand our definition of people who are sensitive to these types of agents,” Reiss said. “It may be not just for cancer patients with germline BRCA mutations. PARP inhibition could work with ATM, CHK2, and other changes,” she said. “We need to figure out the extent of the population for whom these drugs may be helpful.” ... "