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" ... Reh noted that organoids do not develop foveae either, and because the organoids are much smaller than human retinas and don’t develop the other cell types of the retina in the appropriate ratio to cones, the changes in thyroid hormone levels might be different in the experiments than in developing retinas. “In some ways it is amazing that developmental processes as complex as cone specification work as well as they do given the caveats,” he wrote. ... "