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" ... Among flaviviruses -- a group that includes Zika, yellow fever and West Nile virus -- it's rare for a virus to be transmitted from one generation to the next. Scientists believe that's because the organ connecting mother and fetus -- the placenta -- forms a barrier between the two individuals, separating their circulatory systems. ... "
" ... Preliminary results suggest that individuals who have already been exposed to certain types of flaviviruses, and therefore have some form of viral immunity, may need less dosing of MZ4 to obtain a measurable immune effect. For example, when volunteers with pre-existing dengue exposure were able to elicit a Zike antibody response after only one dose. However, those without pre-exposure needed a second dose to elicit the same. ... "