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" ... In recent years, though, some drugs that lower cholesterol have turned out to hurt patients. Torcetrapib, an experimental Pfizer drug that cut LDL and boosted HDL, the so-called "good cholesterol", actually increased the death rate in a large study and was never approved. Niacin, one of the first LDL-lowerers and also an HDL-booster, was recommended by doctors for years. But a Merck trial on a new formulation showed no benefits and some potential harms. Data about other potential drugs, like fish oil supplements or drugs called fibrates, have been inconclusive. ... "