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" ... Spravato is the brand name for esketamine, a molecular mirror-image of ketamine that’s three times more potent but can be given at a lower dose, as a nasal spray rather than injection. “We are going to try and make it very accessible to patients, as much as we can,” said Husseini Manji, global head of neuroscience therapeutics for Janssen Research & Development, a division of Johnson & Johnson, in an interview before the FDA approval announcement. ... "
" ... “There is no such thing as a drug for everyone,” explained Dr. Cristina Cusin, a Harvard based psychiatrist who has been involved with esketamine trials in the past but was not involved with the most recent ASPIRE trials. “If you think of any medical condition, there is no such thing as a drug for everybody.” ... "