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" ... “What’s often lost on people is how incredible it is that we find any human medicines at all. Every human being is 40 trillion cells, working together. We understand a fraction of the proteins, what they do. 1200 drugable proteins, there’s only a fraction of those we can actually drug. We don’t know what most of RNA does, non-coding RNA, we don’t know most of what the genome is even talking about. Since the creation of FDA there’s only been about 1500 new molecular entities ever found, and most of those are overlapping in similar therapeutic areas. If you account for double counts, my guess is it’s in the hundreds of medicines that we’ve actually found. ... "