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" ... Hostetler also didn’t have a complete answer, although he noted that the lab and David Evans at Edmonton looked at how the drug gets incorporated into the virus's DNA versus human DNA. Perhaps the viral DNA damage cannot be repaired as easily as the human DNA damage. We do know that cidofovir (in its activated, diphosphate form) does inhibit CMV's viral DNA polymerase about eight times more effectively than human DNA polymerase alpha. I’m certain that researchers will have to come back to this question. ... "