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" ... Interstitial cystitis (IC) is a cause of unrelenting pain in the bladder and pelvic regions of the lower abdomen. It’s estimated that at least 1 million people, mostly women, in the U.S. have this painful condition. While other pharmacologic (NSAIDS, antihistamines, bladder installation therapy) and behavioral approaches are available, Elmiron is the only FDA-approved medication to treat this painful and disabling condition. It effectively works by forming a protective coating on the inner lining of the bladder that reduces irritation by substances present in the urine. Since it’s a first-line drug used for many decades, it’s believed that at least several hundred of thousand people have likely been exposed to the drug. ... "
" ... Phexxi was tested on 1,400 women who were aged between 18 to 35. It was 86 percent effective on average over seven menstrual cycles. A small minority of women suffered from cystitis, pyelonephritis, and UTI’s afterward and Evofem has suggested that Phexxi isn’t suitable for people with a history of recurrent urinary tract infections or urinary tract abnormalities. ... "
" ... The first application, currently in clinical development, is to treat interstitial cystitis (IC), a painful bladder disease in women that forces them to urinate every 10 minutes. LiRIS delivers a steady dose of a well-known local anesthetic, Lidocaine, that relieves IC's symptoms. ... "