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" ... So the risk of serotonin syndrome from taking both drugs is roughly that of dying in a motor vehicle crash. This is important information for doctors, pharmacists and other caregivers to consider with patients who have the need to take both classes of drugs. The researchers calculated 21% to 29% of patients in the study had the need for coprescription of these drugs. Interestingly, that range remained constant even after the FDA's 2006 advisory, suggesting that it didn't alter the number of patients who needed both drugs from getting them. ... "