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" ... The UCLA outbreak, and the worse one with the newly reported colistin resistance in Pittsburgh are signs that we are approaching the end of the era of antibiotics. There are numerous reasons for this ranging from physicians not wanting restrictions on their prescribing patterns, to pharma's detailing drugs irresponsibly, to our seeming current belief that there will always be a new “miracle drug” just around the corner, to the misuse of antibiotics in agriculture to the ready availability of antibiotics “over-the-counter' without prescription in many countries. The bottom line is that it appears that we are all too rapidly headed back to the pre-antibiotic era, when even a minor scratch could be a death sentence. ... "