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" ... A couple of years ago, I was faced with a patient who was likely to die of sepsis if she did not undergo emergency surgery to remove her colon (colectomy). I wondered why no one was doing fecal transplants in such acutely ill patients, as the technique is successful in treating patients suffering with less virulent and chronic infection. I offered this option to the patient’s family, explaining that it was totally unconventional and “off-label,” but might work. They agreed. Unfortunately, the patient had discomfort with the initial effort (instillation via enema), so we did not continue, and she died soon thereafter. ... "