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" ... Butterfly’s challenge is now finding their market. I tried out the device, which took me down memory lane, searching for a vein to insert an imaginary central line, using the doppler to check I wasn’t about to hit the carotid artery. And I was impressed. I can see my previous anaesthetic colleagues using it to perform nerve blocks before surgeries, difficult lines and as a teaching tool among other things; not least because the current portable scanners are often too bulky for a small anaesthetic room. The fact that they can afford it personally and keep it with them also means there is likely to be a B2C market bypassing any central procurement by hospitals. Similarly, senior physicians comfortable with POCUS in specialties like respiratory and cardiology could use the device in their clinics, but POCUS is a special skill that only certain physicians learn. A culture shift to embrace POCUS will need to accompany the adoption of the Butterfly iQ device if it is to reach its potential and sell at huge scale. ... "
" ... Oxygen makes up approximately one fifth of Earth’s atmosphere. It can be harmful if concentrations in the body are too high and, we can all agree, deadly when too low, so tight control of how much oxygen our cells receive is critical. Otto Warburg, the recipient of the 1931 Nobel Prize in Physiology or Medicine, revealed that oxygen is used by our cells to convert food into energy in an enzymatic process. The 1938 Nobel Prize in Physiology or Medicine was then awarded to Corneille Heymans who showed how the carotid body in our neck communicates with our brain to sense oxygen levels and change our breathing rate. Since the beginning of the 20th century we have known that low oxygen causes a rise in the hormone erythropoietin (EPO), which produces more red blood cells, but exactly how cells adapted to changes in levels of oxygen remained a mystery until now. ... "
" ... The harpoon was apparently quite close to the carotid artery, a vital artery that supplies blood to the brain. Interruption of this blood vessel can lead to death or a stroke, depending on severity of the injury. ... "
" ... Therefore, like a well-run city, your body needs ways of sensing what’s going on in each of the neighborhoods and adjusting oxygen levels accordingly. One way of adjusting your body’s oxygen supply in general is by changing your breathing rate. The carotid arteries are the major blood vessels in your neck and the ones that often spurt blood in slasher horror movies. These arteries include structures called carotid bodies that can check the oxygen levels in the passing blood. If oxygen levels are too low, the carotid bodies sends signals through nerves to increase your breathing rate. If the oxygen levels are too high, the carotid bodies will signal to slow your breathing. While this may help the overall amount of oxygen getting into your lungs and blood circulation, it alone can’t monitor and adjust the oxygen that’s getting to more local levels throughout your body. ... "