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" ... The first type includes a re-engineered canarypox virus combined with pieces of HIV that can’t cause HIV infection on their own. This is the priming part of the vaccine, the portion that primes or alerts your immune to the virus, telling your immune system, “this is your enemy, this is what you should be defending against.” It is, in a way, the canarypox in the coal mine that warns your defense system. The second type of injection consists of pieces of the protein envelope that surround the HIV along with M59, an adjuvant that uses an organic compound called squalene. An adjuvant is a substance that doesn’t on its own generate immune responses but instead can boost your immune system’s responses to parts of the virus. This is the boost part of the so-called “prime-boost” strategy. Once the the immune system is alerted to the virus, this part boosts the troops, which are your immune system’s B cells. Kind of like recruiting Captain Marvel, Ant Man, and others to the cause to fight Thanos. ... "