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" ... The application for this patent was first filed in 1990 and has been rejected, modified, re-submitted, opposed, and updated during the course of its prosecution. Now, with its issuance, however, Amgen appear to have a formidable piece of IP to defend against the incursions of erstwhile "biosimilar" or "biogeneric" competitors. Contrary to our initial quick take, conversations with the three involved parties (Roche, Amgen, Pfizer) suggest that the sunsetting of Amgen's profit sharing obligation on Enbrel to Pfizer in the 2013-2015 period are unaffected by this patent, and Roche is not entitled to any royalties on Enbrel now or in the future. As such, this patent offers more upside than our initial cautious assessment. ... "