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" ... Milanova says that her team atomizes the CBD so it stays on the surface of the tampon, where it’s in contact with the vaginal mucosa, which is saturated with cannabinoid receptors. When agents are administered vaginally, they are processed through the first pass uterine effect, rather than systemically, which means they are recycled through the pelvic organs and do not have an impact on the digestive system, kidneys or liver. ... "