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" ... Returning to the archaeological context, it interests Haddow and colleagues that B21 was buried quite differently than everyone else. Both the orientation of the grave and the artifacts included in it may, they say, “reflect societal recognition of this individual’s conspicuous intersex status,” which could be the result of pre-pubertal castration but might also reflect a condition such as Klinefelter Syndrome or aromatase deficiency. B26, however, was buried in a similar manner to everyone else. “Perhaps this individual’s condition did not result in visibly ambiguous sexual characteristics,” the researchers suggest. ... "
" ... Some details: The median age was 65 years at enrollment. All participants had received, and tolerated, an aromatase inhibitor for approximately 5 years after an early-stage, ER-positive breast cancer diagnosis, with no evidence of disease. Most had previously received tamoxifen, and half of the women were 10 years “out” from the initial breast cancer diagnosis. The two study arms, each with 959 women, were balanced in terms of prior tamoxifen exposure, lymph node involvement (just over half of the women had at least one positive node) and other factors. ... "