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" ... A possible explanation for the elevated levels, not offered by the authors, is that antibodies related to SARS-CoV-2 itself, or to infected cells or cell debris, triggers an autoimmune reaction similar to that found in lupus patients. Other researchers have recently reported favorable outcomes in patients treated with anticoagulants. ... "
" ... According to the companies, approximately 719,000 total knee replacement surgeries and 332,000 hip replacement surgeries are performed each year in the US. The use of anticoagulants are recommended in these patients because they are at elevated risk for developing DVT and PE. ... "
" ... Here I describe just such an example. Should patients hospitalized for Covid-19 be treated with anticoagulants as early as possible, or should treatment be delayed until clinical signs indicate that hyper-coagulation is likely? This is just one of the many judgments caregivers must make in facing a new complex disease such as Covid-19. ... "
" ... Regarding our own practice, we routinely use bleeding avoidance strategies (appropriate dosing, targeted anticoagulants, radial access) in order to reduce the risk for transfusion post PCI. In patients who are stable post PCI (no chest pain, no active bleeding) we follow our transfusion protocol that recommends transfusion only if the hemoglobin is equal to or less than 8 g/dl ( hct equal to or less than 24%). This is based on other observational data and as we mention in the paper, these data can be subject to confounding. So we really need randomized trial data to guide practice. ... "
" ... The study results "add to the evidence that the new oral anticoagulants are simple alternatives to conventional therapy for patients with acute venous thromboembolism," the authors wrote. ... "